Regulation of the activator protein-1 members and cell cycle by ultraviolet radiation and its modulation by retinoid pre-treatment in keratinocytes - by Lara Helmi El Touni

Abstract

Skin cancer, the most prevalent malignancy, and photoaging result from accumulated damage caused by repeated exposures to solar irradiation in the UVB range. Retinoids regulate epidermal cell proliferation and differentiation in vivo and in vitro, and are