Skin cancer is the most prevalent malignancy in humans. Its chief cause is chronic exposure to ultraviolet-B radiation (UVB). An accumulating body of evidence shows that retinoid receptors, the nuclear receptors for retinoic ...
Ultraviolet radiation is the most common environmental factor in the pathogenesis of skin cancer. It is known to induce programmed cell death (apoptosis) via many pathways one of which is the production of reactive oxygen ...
Irradiation of hairless mice with ultraviolet B (UVB) resulted in a dramatic time-dependent and dose-dependent increase in epidermal ornithine decarboxylase (ODC) activity and DNA synthesis, two short-term biochemical ...
Skin cancer, the most prevalent malignancy, and photoaging result from accumulated damage caused by repeated exposures to solar irradiation in the UVB range. Retinoids regulate epidermal cell proliferation and differentiation ...