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Browsing Pediatrics and Adolescent Medicine - Faculty Publications by Issue Date

Now showing items 1-20 of 321

Impaired cell adhesion and apoptosis in a novel CLN9 Batten disease variant

Schulz A.; Dhar S.; Rylova S.; Dbaibo G.; Alroy J.; Hagel C.; Artacho I.; Kohlschutter A.; Lin S.; Boustany R.-M. (HOBOKENDIV JOHN WILEY and SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA, 2004)

We describe the ninth variant of neuronal ceroid lipofuscinosis (NCL) or Batten disease, due to defects in a putative new gene, CLN9. We therefore refer to the new variant as CLN9-deficient. Two Serbian sisters and two ...
Down-regulation of sphingosine kinase-1 by DNA damage: Dependence on proteases and p53

Taha T.A.; Osta W.; Kozhaya L.; Bielawski J.; Johnson K.R.; Gillanders W.E.; Dbaibo G.S.; Hannun Y.A.; Obeid L.M. (BETHESDA9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA, 2004)

Sphingosine kinase 1 (SK1), a key enzyme in sphingosine 1-phosphate (S1P) synthesis, regulates various aspects of cell behavior, including cell survival and proliferation. DNA damaging anti-neoplastic agents have been shown ...
Impact of maternal age on preterm delivery and low birthweight: A hospital-based collaborative study of nulliparous Lebanese women in Greater Beirut

Beydoun, H.; Itani, M.; Tamim, H.; Aaraj, A.; Yunis, K.; Alameh, M.; Chedid, P.; Chokr, I.; Itani, M.; Khogali, M.; Melki, I.; Nassif, F.; Nassif, Y.; Rajab, M.; Wakim, G. (, 2004)

Objectives: To analyze the impact of maternal age at first childbirth on the incidence of preterm delivery and low birthweight among single live births delivered to nulliparous Lebanese women in Greater Beirut. Study Design: ...
Risk factors for term or near-term fetal growth restriction in the absence of maternal complications

Yunis K.A.; Beydoun H.; Tamim H.; Nassif Y.; Khogali M. (NEW YORK333 SEVENTH AVE, NEW YORK, NY 10001 USA, 2004)

The objective of this study was to examine risk factors for term or near-term fetal growth restriction (FGR) in the absence of pregnancy complications. We completed a survey of uncomplicated single live births delivered ...
Specific HLA-DRB and -DQB Alleles and Haplotypes Confer Disease Susceptibility or Resistance in Bahraini Type 1 Diabetes Patients

Al-Harbi E.M.; Abbassi A.-J.; Tamim H.; Al-Jenaidi F.; Kooheji M.; Kamal M.; Al-Mahroos S.; Al-Nasir F.; Motala A.A.; Almawi W.Y. (WASHINGTON1752 N ST NW, WASHINGTON, DC 20036-2904 USA, 2004)

Insofar as genetic susceptibility to type 1 diabetes is associated with HLA class II genes, with certain allelic combinations conferring disease susceptibility or resistance, this study assessed the distributions of HLA-DR ...
Magnetic resonance angiography in children with sickle cell disease and abnormal transcranial Doppler ultrasonography findings enrolled in the STOP study

Abboud M.R.; Cure J.; Granger S.; Gallagher D.; Hsu L.; Wang W.; Woods G.; Berman B.; Brambilla D.; Pegelow C.; Lewin J.; Zimmermann R.A.; Adams R.J. (WASHINGTON1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA, 2004)

The stroke prevention study in sickle cell disease (STOP) demonstrated a 90percent reduction in stroke risk with transfusion among patients with time-averaged mean cerebral blood velocity (TAMV) of 200 cm-s or more as ...
A Grid to Assess the Nutritional Status of Low-Birth-Weight Infants in the Neonatal Period

Mounla N. (NEW YORK333 SEVENTH AVE, NEW YORK, NY 10001 USA, 2004)

Growth curves of low-birth-weight infants updated over the past 50 years accept many exclusions and do not provide a standard way to assess the nutritional status of these infants regardless of their diseases in the neonatal ...
Transesophageal Echocardiography Improves Risk Assessment of Thrombolysis of Prosthetic Valve Thrombosis: Results of the International PRO-TEE Registry

Tong A.T.; Roudaut R.; Ozkan M.; Sagie A.; Shahid M.S.A.; Pontes Jr. S.C.; Carreras F.; Girard S.E.; Arnaout S.; Stainback R.F.; Thadhani R.; Zoghbi W.A. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2004)

OBJECTIVES: The goal of this study was to evaluate whether quantitation of thrombus burden with transesophageal echocardiography (TEE) can help risk-stratify patients undergoing thrombolysis of prosthetic valve thrombosis ...
Bone mineral density by age, gender, pubertal stages, and socioeconomic status in healthy Lebanese children and adolescents

Arabi A.; Nabulsi M.; Maalouf J.; Choucair M.; Khalife H.; Vieth R.; El-Hajj Fuleihan G. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2004)

Gender, ethnicity, and lifestyle factors affect bone mass acquisition during childhood, thus the need for age- and sex-adjusted Z scores using ethnic-specific data for bone mineral density (BMD) measurement. This study ...
Bone mineralization in newborns whose mothers received magnesium sulphate for tocolysis of premature labour

Malaeb S.N.; Rassi A.I.; Haddad M.C.; Seoud M.A.; Yunis K.A. (NEW YORK175 FIFTH AVE, NEW YORK, NY 10010 USA, 2004)

Prolonged maternal magnesium sulphate infusion therapy for tocolysis of premature labour may result in secondary fetal hypermagnesaemia, which has been associated with bony abnormalities in the newborn. We report on four ...
Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats

Mikati M.A.; Holmes G.L.; Werner S.; Bakkar N.; Carmant L.; Liu Z.; Stafstrom C.E. (SAN DIEGO525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2004)

Objective. The goal of this study was to investigate the potential protective effects of nimodipine (ND), a calcium channel blocker, on the acute manifestations and long-term behavioral sequalae of experimental status ...
Ceramide inhibits IL-2 production by preventing protein kinase C-dependent NF-κB activation: Possible role in protein kinase Cθ regulation

Abbonshi N.; El-Hed A.; El-Assaad W.; Kozhaya L.; El-Sabban M.E.; Bazarbachi A.; Badreddine R.; Bielawska A.; Usta J.; Dbaibo G.S. (, 2004)

The role of the sphingolipid ceramide in modulating the immune response has been controversial, in part because of conflicting data regarding its ability to regulate the transcription factor NF-κB. To help clarify this ...
N-(4-hydroxyphenyl)retinamide induces growth arrest and apoptosis in HTLV-I-transformed cells

Darwiche N.; Hatoum A.; Dbaibo G.; Kadara H.; Nasr R.; Abou-Lteif G.; Bazzi R.; Hermine O.; de The H.; Bazarbachi A. (LONDONMACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2004)

N-(4-hydroxyphenyl)retinamide (HPR) is a synthetic retinoid that inhibits growth and induces apoptosis in many human cell lines. We explored the effects of HPR on human T-cell lymphotropic virus type I (HTLV-I)-positive ...
Sex differences in the effect of body-composition variables on bone mass in healthy children and adolescents.

Arabi A.; Tamim H.; Nabulsi M.; Maalouf J.; Khalife H.; Choucair M.; Vieth R.; El-Hajj Fuleihan G. (CHEVY CHASE8401 CONNECTICUT AVE, SUITE 900, CHEVY CHASE, MD 20815-5817 USA, 2004)

BACKGROUND: Prophylactic interventions against osteoporosis require a determination of the factors that influence the accumulation of bone mass during growth. OBJECTIVE: The objective was to determine the independent ...
Neuronal Cell Death in a Rat Model of Mesial Temporal Lobe Epilepsy Is Induced by the Initial Status Epilepticus and Not by Later Repeated Spontaneous Seizures (multiple letters)

Mikati M.; Gorter J.A. (, 2004)

[No abstract available]
Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats

Mikati M.A.; Kurdi R.M.; Rahmeh A.M.; Farhat F.; Rialy S.A.; Lteif L.; Francis E.; Geha G.; Maraashli W. (ABINGDON4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND, 2004)

Purpose: To investigate if energy precursor supplementation is neuroprotective in two neuroexcitotoxicity models; the kainate and the kainate followed by chronic phenobarbital models. Methods: Rats in experiment 1 received ...
Household crowding index: A correlate of socioeconomic status and inter-pregnancy spacing in an urban setting

Melki I.S.; Beydoun H.A.; Khogali M.; Tamim H.; Yunis K.A. (LONDONBRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND, 2004)

Objectives: This paper examines the effect of household crowding on inter-pregnancy spacing and its association with socioeconomic indicators, among porous mothers delivered in an urban environment. Design: Cross sectional ...
Predicting neonatal outcomes: Birthweight, body mass index or ponderal index?

Tamim H.; Beydoun H.; Itani M.; Khogali M.; Chokr I.; Yunis K.A. (BERLINGENTHINER STRASSE 13, D-10785 BERLIN, GERMANY, 2004)

Aims: To compare birthweight (BW), body mass index (BMI) and ponderal index (PI) as predictors of selected short-term (ST) outcomes, namely Neonatal Intensive Care Unit (NICU) admission and prolonged hospitalization (PH), ...
Clinical presentation and treatment outcome of children with Burkitt lymphoma in Lebanon: A single institution's experience

Muwakkit S.A.; Razzouk B.I.; Shabb N.S.; Hancock M.L.; Dabbous I.; Firzli S.; Abboud M.R. (PHILADELPHIA530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2004)

The authors reviewed the medical records of 42 children younger than 13 years of age diagnosed with Burkitt lymphoma at the American University of Beirut Medical Center between 1983 and 1993. The male:female ratio was 3.9. ...
Erratum: Stages of status epilepticus in the developing brain (Epilepsy Research (2003) 55 (9-19) DOI: 10.1016-S0920-1211(03)00089-5)

Mikati M.A.; Werner S.; Shalak L.; Shamseddine A.; Simaan E.; Liu Z.; Tarif S.; Stafstrom C.; Holmes G. (AMSTERDAMPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2005)

[No abstract available]

Now showing items 1-20 of 321

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Browsing Pediatrics and Adolescent Medicine - Faculty Publications by Issue Date

Browsing Pediatrics and Adolescent Medicine - Faculty Publications by Issue Date

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